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What does alcohol do to your liver? The science behind liver values

25 March 2026 4 min lezen
Wat doet alcohol met je lever?
Liver and alcohol metabolism โ€” metabolic pathway from ethanol to acetaldehyde to acetate
๐Ÿ”ฌ Liver & Alcohol

What does alcohol do to your liver?
The science behind liver values

Reading time: 6 minutes ย ยทย  Scientifically supported
90%of alcohol is
broken down in the liver
80%glutathione decrease in
chronic alcohol use
1 hourper standard-
glass processing time

Your liver is one of the hardest working organs in your body. Every day it filters waste, produces proteins, and regulates your blood sugar. But when it comes to alcohol, the liver faces a special challenge โ€” one that, with regular use, leaves its marks.

โš—๏ธ How does the liver process alcohol?

As soon as you drink a glass of wine or beer, the alcohol is absorbed into the blood through the stomach and small intestine and transported to the liver. The liver is responsible for breaking down about 90% of all consumed alcohol. This process occurs in two steps.

1
Alcohol โ†’ Acetaldehyde (via ADH enzyme)

The enzyme alcohol dehydrogenase (ADH) converts alcohol into acetaldehyde. This substance is 10โ€“30ร— more toxic than alcohol itself and causes most of the cell damage.

2
Acetaldehyde โ†’ Acetate (via ALDH enzyme)

Acetaldehyde is further broken down into the relatively harmless acetate, which the body can use as an energy source. This process requires glutathione.

๐Ÿ’ก Did you know?

The liver can process on average only one standard drink of alcohol per hour. If you drink faster, the toxic acetaldehyde accumulates in the blood โ€” and you feel it the next morning.

๐Ÿฉบ What are liver values and what do they indicate?

Liver values are blood values that doctors use to assess how well the liver is functioning. When liver cells are damaged, these enzymes leak into the bloodstream โ€” a signal that the liver is working harder than usual.

Liver value What it measures Normal value
ALAT (ALT) Liver cell damage < 45 U/L
ASAT (AST) Liver and muscle cell damage < 40 U/L
GGT (gamma-GT) Gallstones and alcohol consumption < 55 U/L
Bilirubin Breakdown of red blood cells < 17 ยตmol/L
๐Ÿ“ˆ What does regular alcohol use do to the liver?

Occasional drinking gives the liver time to recover. But with regular or excessive use, a pattern of damage can develop in three stages:

1
Fatty liver (steatosis)

The liver stores fat as a byproduct of alcohol metabolism. Fully reversible in an early stage with alcohol reduction.

2
Alcoholic hepatitis

With persistent excessive use, liver cells can become inflamed. Accompanied by fatigue, nausea, and sometimes pain in the upper right abdomen.

3
Liver cirrhosis

Liver tissue is replaced by scar tissue. Largely irreversible and structurally impairs liver function.

๐Ÿ›ก๏ธ The role of glutathione in alcohol metabolism

A key figure in liver protection is glutathione โ€” the most common antioxidant in the human body. Glutathione neutralizes the toxic acetaldehyde and free radicals released during alcohol metabolism.

80%
Decrease in glutathione with chronic alcohol use
600mg
NAC per day supports glutathione production
3ร—
Active ingredients in Livera Shield
โš ๏ธ Vicious cycle

The more alcohol, the less glutathione is available for protection โ€” and the more damage the liver sustains. NAC supplementation helps break this cycle by replenishing glutathione stores.

โœ… What can you do to support your liver?

Besides moderating alcohol consumption, proven strategies to actively support the liver include cruciferous vegetables (broccoli, Brussels sprouts) for sulforaphane, adequate hydration, and targeted supplements like NAC (600 mg/day) for glutathione support.

Support your liver daily

Livera Shield combines 600 mg NAC, glutathione, and BroccoPhaneยฎ for broad liver support โ€” scientifically proven, suitable for daily use.

View Livera Shield โ†’
Dietary supplement ยท Not a medical product

Livera Shield is a dietary supplement. This product does not replace medical advice. Consult a doctor if you have complaints or questions about your liver values.

Livera Shield

Ondersteun je lever dagelijks

NAC 400mg ยท Milk Thistle 120mg ยท BoccShieldโ„ข 70mg

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